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ADS024, a Bacillus velezensis strain, protects human colonic epithelial cells against C. difficile toxin-mediated apoptosis

Clostridioides difficile infection (CDI) causes intestinal injury. Toxin A and toxin B cause intestinal injury by inducing colonic epithelial cell apoptosis. ADS024 is a Bacillus velezensis strain in development as a single-strain live biotherapeutic product (SS-LBP) to prevent the recurrence of CDI...

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Detalles Bibliográficos
Autores principales: Xie, Ying, Chupina Estrada, Andrea, Nelson, Becca, Feng, Hanping, Pothoulakis, Charalabos, Chesnel, Laurent, Koon, Hon Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873417/
https://www.ncbi.nlm.nih.gov/pubmed/36704560
http://dx.doi.org/10.3389/fmicb.2022.1072534