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Melatonin Repairs Osteoporotic Bone Defects in Iron-Overloaded Rats through PI3K/AKT/GSK-3β/P70S6k Signaling Pathway

It was found recently that iron overload can cause osteoporosis in rats. Through in vitro and in vivo experimentations, the purpose of the present study was to validate and confirm the inhibitory effects of melatonin on iron death of osteoporosis and its role in bone microstructure improvements. Mel...

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Detalles Bibliográficos
Autores principales: Ren, Maoxian, Liu, Hedong, Jiang, Wenkai, Zhou, Zhi, Yao, Xuewei, Liu, Zhiyi, Ma, Nengfeng, Chen, Bing, Yang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873465/
https://www.ncbi.nlm.nih.gov/pubmed/36703914
http://dx.doi.org/10.1155/2023/7718155