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Central role for BRAF in cardiac hypertrophy: rethinking the pathological–physiological divide

The RAF/MEK/ERK1/2 signaling cascade has been implicated in pathological cardiac hypertrophy downstream of some Gq-coupled receptors. The RAF family of kinases consists of three isoforms (ARAF, BRAF, and CRAF) and until recently most studies on this signaling pathway in the heart have focused on RAF...

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Detalles Bibliográficos
Autores principales: Altara, Raffaele, Booz, George W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873497/
https://www.ncbi.nlm.nih.gov/pubmed/36651286
http://dx.doi.org/10.1042/CS20220776