Computational approach to evaluate scRNA-seq data quality and gene body coverage with SkewC

SkewC is a single-cell RNA sequencing (scRNA-seq) data quality evaluation tool. The approach is based on determining gene body coverage, and its skewness, as a quality metric for each individual cell. SkewC distinguishes between two types of single cells: typical cells with prototypical gene body co...

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Detalles Bibliográficos
Autores principales: Abugessaisa, Imad, Hasegawa, Akira, Katayama, Shintaro, Kere, Juha, Kasukawa, Takeya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873502/
https://www.ncbi.nlm.nih.gov/pubmed/36853658
http://dx.doi.org/10.1016/j.xpro.2022.102038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873502/
https://www.ncbi.nlm.nih.gov/pubmed/36853658
http://dx.doi.org/10.1016/j.xpro.2022.102038

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