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Computational approach to evaluate scRNA-seq data quality and gene body coverage with SkewC
SkewC is a single-cell RNA sequencing (scRNA-seq) data quality evaluation tool. The approach is based on determining gene body coverage, and its skewness, as a quality metric for each individual cell. SkewC distinguishes between two types of single cells: typical cells with prototypical gene body co...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873502/ https://www.ncbi.nlm.nih.gov/pubmed/36853658 http://dx.doi.org/10.1016/j.xpro.2022.102038 |