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Effects of APOE ε2 allele on basal forebrain functional connectivity in mild cognitive impairment

BACKGROUND: Basal forebrain cholinergic system (BFCS) dysfunction is associated with cognitive decline in Alzheimer's disease (AD) and mild cognitive impairment (MCI). Apolipoprotein E (APOE) ε2 is a protective genetic factor in AD and MCI, and cholinergic sprouting depends on APOE. OBJECTIVE:...

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Detalles Bibliográficos
Autores principales: Liu, Xiaocao, Zeng, Qingze, Luo, Xiao, Li, Kaicheng, Xu, Xiaopei, Hong, Luwei, Li, Jixuan, Guan, Xiaojun, Xu, Xiaojun, Huang, Peiyu, Zhang, Min‐Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873529/
https://www.ncbi.nlm.nih.gov/pubmed/36468416
http://dx.doi.org/10.1111/cns.14038