T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection

Antigen-specific, MHC-restricted αβ T cells are necessary for protective immunity against Mycobacterium tuberculosis, but the ability to broadly study these responses has been limited. In the present study, we used single-cell and bulk T cell receptor (TCR) sequencing and the GLIPH2 algorithm to ana...

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Detalles Bibliográficos
Autores principales: Musvosvi, Munyaradzi, Huang, Huang, Wang, Chunlin, Xia, Qiong, Rozot, Virginie, Krishnan, Akshaya, Acs, Peter, Cheruku, Abhilasha, Obermoser, Gerlinde, Leslie, Alasdair, Behar, Samuel M., Hanekom, Willem A., Bilek, Nicole, Fisher, Michelle, Kaufmann, Stefan H. E., Walzl, Gerhard, Hatherill, Mark, Davis, Mark M., Scriba, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873565/
https://www.ncbi.nlm.nih.gov/pubmed/36604540
http://dx.doi.org/10.1038/s41591-022-02110-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873565/
https://www.ncbi.nlm.nih.gov/pubmed/36604540
http://dx.doi.org/10.1038/s41591-022-02110-9

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