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T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection
Antigen-specific, MHC-restricted αβ T cells are necessary for protective immunity against Mycobacterium tuberculosis, but the ability to broadly study these responses has been limited. In the present study, we used single-cell and bulk T cell receptor (TCR) sequencing and the GLIPH2 algorithm to ana...
Autores principales: | Musvosvi, Munyaradzi, Huang, Huang, Wang, Chunlin, Xia, Qiong, Rozot, Virginie, Krishnan, Akshaya, Acs, Peter, Cheruku, Abhilasha, Obermoser, Gerlinde, Leslie, Alasdair, Behar, Samuel M., Hanekom, Willem A., Bilek, Nicole, Fisher, Michelle, Kaufmann, Stefan H. E., Walzl, Gerhard, Hatherill, Mark, Davis, Mark M., Scriba, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873565/ https://www.ncbi.nlm.nih.gov/pubmed/36604540 http://dx.doi.org/10.1038/s41591-022-02110-9 |
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