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Polyamine metabolism impacts T cell dysfunction in the oral mucosa of people living with HIV

Metabolic changes in immune cells contribute to both physiological and pathophysiological outcomes of immune reactions. Here, by comparing protein expression, transcriptome, and salivary metabolome profiles of uninfected and HIV+ individuals, we found perturbations of polyamine metabolism in the ora...

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Detalles Bibliográficos
Autores principales: Mahalingam, S. S., Jayaraman, S., Bhaskaran, N., Schneider, E., Faddoul, F., Paes da Silva, A., Lederman, M. M., Asaad, R., Adkins-Travis, K., Shriver, L. P., Pandiyan, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873639/
https://www.ncbi.nlm.nih.gov/pubmed/36693889
http://dx.doi.org/10.1038/s41467-023-36163-2