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Molecular dynamics study of Cl(−) permeation through cystic fibrosis transmembrane conductance regulator (CFTR)
The recent elucidation of atomistic structures of Cl(−) channel CFTR provides opportunities for understanding the molecular basis of cystic fibrosis. Despite having been activated through phosphorylation and provided with ATP ligands, several near-atomistic cryo-EM structures of CFTR are in a closed...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873711/ https://www.ncbi.nlm.nih.gov/pubmed/36694009 http://dx.doi.org/10.1007/s00018-022-04621-7 |