USP14 promotes colorectal cancer progression by targeting JNK for stabilization

MAPK/JNK signaling is pivotal in carcinogenesis. However, ubiquitin-mediated homeostasis of JNK remains to be verified. Here, with results from RNA sequencing (RNA-seq) and luciferase reporter pathway identification, we show that USP14 orchestrates MAPK/JNK signaling and identify USP14 as a deubiqui...

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Detalles Bibliográficos
Autores principales: Du, Xue-Hua, Ke, Shao-Bo, Liang, Xin-Yi, Gao, Jie, Xie, Xiao-Xiao, Qi, Lin-Zhi, Liu, Xue-Yi, Xu, Guo-Yuan, Zhang, Xiao-Dong, Du, Run-Lei, Li, Shang-Ze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873792/
https://www.ncbi.nlm.nih.gov/pubmed/36693850
http://dx.doi.org/10.1038/s41419-023-05579-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873792/
https://www.ncbi.nlm.nih.gov/pubmed/36693850
http://dx.doi.org/10.1038/s41419-023-05579-5

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