Fc effector of anti-Aβ antibody induces synapse loss and cognitive deficits in Alzheimer’s disease-like mouse model

Passive immunotherapy is one of the most promising interventions for Alzheimer’s disease (AD). However, almost all immune-modulating strategies fail in clinical trials with unclear causes although they attenuate neuropathology and cognitive deficits in AD animal models. Here, we showed that Aβ-targe...

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Detalles Bibliográficos
Autores principales: Sun, Xiao-ying, Yu, Xiao-lin, Zhu, Jie, Li, Ling-jie, Zhang, Lun, Huang, Ya-ru, Liu, Dong-qun, Ji, Mei, Sun, Xun, Zhang, Ling-xiao, Zhou, Wei-wei, Zhang, Dongming, Jiao, Jianwei, Liu, Rui-tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873795/
https://www.ncbi.nlm.nih.gov/pubmed/36693826
http://dx.doi.org/10.1038/s41392-022-01273-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873795/
https://www.ncbi.nlm.nih.gov/pubmed/36693826
http://dx.doi.org/10.1038/s41392-022-01273-8

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