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Fc effector of anti-Aβ antibody induces synapse loss and cognitive deficits in Alzheimer’s disease-like mouse model

Passive immunotherapy is one of the most promising interventions for Alzheimer’s disease (AD). However, almost all immune-modulating strategies fail in clinical trials with unclear causes although they attenuate neuropathology and cognitive deficits in AD animal models. Here, we showed that Aβ-targe...

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Detalles Bibliográficos
Autores principales:	Sun, Xiao-ying, Yu, Xiao-lin, Zhu, Jie, Li, Ling-jie, Zhang, Lun, Huang, Ya-ru, Liu, Dong-qun, Ji, Mei, Sun, Xun, Zhang, Ling-xiao, Zhou, Wei-wei, Zhang, Dongming, Jiao, Jianwei, Liu, Rui-tian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873795/ https://www.ncbi.nlm.nih.gov/pubmed/36693826 http://dx.doi.org/10.1038/s41392-022-01273-8

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