Identification of a human estrogen receptor α tetrapeptidic fragment with dual antiproliferative and anti-nociceptive action

The synthetic peptide ERα17p (sequence: PLMIKRSKKNSLALSLT), which corresponds to the 295–311 region of the human estrogen receptor α (ERα), induces apoptosis in breast cancer cells. In mice and at low doses, it promotes not only the decrease of the size of xenografted triple-negative human breast tu...

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Detalles Bibliográficos
Autores principales: Jouffre, Baptiste, Acramel, Alexandre, Belnou, Mathilde, Santolla, Maria Francesca, Talia, Marianna, Lappano, Rosamaria, Nemati, Fariba, Decaudin, Didier, Khemtemourian, Lucie, Liu, Wang-Qing, Maggiolini, Marcello, Eschalier, Alain, Mallet, Christophe, Jacquot, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873809/
https://www.ncbi.nlm.nih.gov/pubmed/36693877
http://dx.doi.org/10.1038/s41598-023-28062-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873809/
https://www.ncbi.nlm.nih.gov/pubmed/36693877
http://dx.doi.org/10.1038/s41598-023-28062-9

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