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Genome-wide association study in a rat model of temperament identifies multiple loci for exploratory locomotion and anxiety-like traits

Common genetic factors likely contribute to multiple psychiatric diseases including mood and substance use disorders. Certain stable, heritable traits reflecting temperament, termed externalizing or internalizing, play a large role in modulating vulnerability to these disorders. To model these herit...

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Detalles Bibliográficos
Autores principales: Chitre, Apurva S., Hebda-Bauer, Elaine K., Blandino, Peter, Bimschleger, Hannah, Nguyen, Khai-Minh, Maras, Pamela, Li, Fei, Ozel, A. Bilge, Pan, Yanchao, Polesskaya, Oksana, Cheng, Riyan, Flagel, Shelly B., Watson, Stanley J., Li, Jun, Akil, Huda, Palmer, Abraham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873817/
https://www.ncbi.nlm.nih.gov/pubmed/36712851
http://dx.doi.org/10.3389/fgene.2022.1003074