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DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma

Glioblastoma (GBM) currently has a dismal prognosis. GBM cells that survive radiotherapy contribute to tumor progression and recurrence with metabolic advantages. Here, we show that diacylglycerol kinase B (DGKB), a regulator of the intracellular concentration of diacylglycerol (DAG), is significant...

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Detalles Bibliográficos
Autores principales: Kang, Hyunkoo, Lee, Haksoo, Kim, Kyeongmin, Shin, Eunguk, Kim, Byeongsoo, Kang, JiHoon, Kim, Bohkyung, Lee, Jung Sub, Lee, Jae-Myung, Youn, HyeSook, Youn, BuHyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873821/
https://www.ncbi.nlm.nih.gov/pubmed/36603576
http://dx.doi.org/10.1016/j.xcrm.2022.100880