Cargando…
DGKB mediates radioresistance by regulating DGAT1-dependent lipotoxicity in glioblastoma
Glioblastoma (GBM) currently has a dismal prognosis. GBM cells that survive radiotherapy contribute to tumor progression and recurrence with metabolic advantages. Here, we show that diacylglycerol kinase B (DGKB), a regulator of the intracellular concentration of diacylglycerol (DAG), is significant...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873821/ https://www.ncbi.nlm.nih.gov/pubmed/36603576 http://dx.doi.org/10.1016/j.xcrm.2022.100880 |