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Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status

High-grade adult-type diffuse gliomas are malignant neuroepithelial tumors with poor survival rates in combined chemoradiotherapy. The current WHO classification is based on IDH1/2 mutational and 1p/19q codeletion status. Glioma proteome alterations remain undercharacterized despite their promise fo...

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Detalles Bibliográficos
Autores principales: Bader, Jakob Maximilian, Deigendesch, Nikolaus, Misch, Martin, Mann, Matthias, Koch, Arend, Meissner, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873829/
https://www.ncbi.nlm.nih.gov/pubmed/36584682
http://dx.doi.org/10.1016/j.xcrm.2022.100877