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Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status
High-grade adult-type diffuse gliomas are malignant neuroepithelial tumors with poor survival rates in combined chemoradiotherapy. The current WHO classification is based on IDH1/2 mutational and 1p/19q codeletion status. Glioma proteome alterations remain undercharacterized despite their promise fo...
Autores principales: | Bader, Jakob Maximilian, Deigendesch, Nikolaus, Misch, Martin, Mann, Matthias, Koch, Arend, Meissner, Felix |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873829/ https://www.ncbi.nlm.nih.gov/pubmed/36584682 http://dx.doi.org/10.1016/j.xcrm.2022.100877 |
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