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Antibodies against type I IFN: The bad guys self-restrain in systemic lupus erythematosus
B cells and autoantibodies have well-described pathological roles in systemic lupus erythematosus (SLE). Bradford et al.(1) now provide evidence that autoantibodies can also be protective by neutralizing type I interferons (IFNs) and restraining the activation of pathogenic B cells.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873922/ https://www.ncbi.nlm.nih.gov/pubmed/36652912 http://dx.doi.org/10.1016/j.xcrm.2022.100903 |