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Antibodies against type I IFN: The bad guys self-restrain in systemic lupus erythematosus

B cells and autoantibodies have well-described pathological roles in systemic lupus erythematosus (SLE). Bradford et al.(1) now provide evidence that autoantibodies can also be protective by neutralizing type I interferons (IFNs) and restraining the activation of pathogenic B cells.

Detalles Bibliográficos
Autor principal: Fillatreau, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873922/
https://www.ncbi.nlm.nih.gov/pubmed/36652912
http://dx.doi.org/10.1016/j.xcrm.2022.100903