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Size matters in non-canonical inflammasome activation and cell-mediated immunity

Particulate adjuvants are key components of many approved vaccines, but their mechanism of adjuvanticity is debated. Muñoz-Wolf et al.(1) find that 50-nm particles maximize cell-mediated immune responses by activating the caspase-11 inflammasome, providing mechanistic insight to particulate adjuvant...

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Detalles Bibliográficos
Autores principales: Weiss, Adam M., Esser-Kahn, Aaron P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873938/
https://www.ncbi.nlm.nih.gov/pubmed/36652913
http://dx.doi.org/10.1016/j.xcrm.2022.100904