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Size matters in non-canonical inflammasome activation and cell-mediated immunity
Particulate adjuvants are key components of many approved vaccines, but their mechanism of adjuvanticity is debated. Muñoz-Wolf et al.(1) find that 50-nm particles maximize cell-mediated immune responses by activating the caspase-11 inflammasome, providing mechanistic insight to particulate adjuvant...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873938/ https://www.ncbi.nlm.nih.gov/pubmed/36652913 http://dx.doi.org/10.1016/j.xcrm.2022.100904 |