Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2

Membrane cholesterol binds to and modulates the function of various SLC6 neurotransmitter transporters, including stabilizing the outward-facing conformation of the dopamine and serotonin transporters. Here, we investigate how cholesterol binds to GlyT2 (SLC6A5), modulates glycine transport rate, an...

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Detalles Bibliográficos
Autores principales: Frangos, Zachary J, Wilson, Katie A, Aitken, Heather M, Cantwell Chater, Ryan, Vandenberg, Robert J, O’Mara, Megan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873984/
https://www.ncbi.nlm.nih.gov/pubmed/36690444
http://dx.doi.org/10.26508/lsa.202201708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873984/
https://www.ncbi.nlm.nih.gov/pubmed/36690444
http://dx.doi.org/10.26508/lsa.202201708

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