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S417 in the CC3 region of STIM1 is critical for STIM1-Orai1 binding and CRAC channel activation
Store-operated Ca(2+) entry (SOCE) is a universal Ca(2+) influx pathway that is important for the function of many cell types. SOCE is controlled by the interaction of the ER Ca(2+) sensor STIM1 with the plasma membrane Ca(2+) channel Orai1. S417 is located in the third coiled-coil (CC3) domain of t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Life Science Alliance LLC
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873985/ https://www.ncbi.nlm.nih.gov/pubmed/36690443 http://dx.doi.org/10.26508/lsa.202201623 |