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Single-Cell Transcriptional Changes in Hypothalamic Corticotropin-Releasing Factor–Expressing Neurons After Early-Life Adversity Inform Enduring Alterations in Vulnerabilities to Stress

BACKGROUND: Mental health and vulnerabilities to neuropsychiatric disorders involve the interplay of genes and environment, particularly during sensitive developmental periods. Early-life adversity (ELA) and stress promote vulnerabilities to stress-related affective disorders, yet it is unknown how...

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Detalles Bibliográficos
Autores principales: Short, Annabel K., Thai, Christina W., Chen, Yuncai, Kamei, Noriko, Pham, Aidan L., Birnie, Matthew T., Bolton, Jessica L., Mortazavi, Ali, Baram, Tallie Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874075/
https://www.ncbi.nlm.nih.gov/pubmed/36712559
http://dx.doi.org/10.1016/j.bpsgos.2021.12.006