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BRPF1 bridges H3K4me3 and H3K23ac in human embryonic stem cells and is essential to pluripotency

Post-translational modifications (PTMs) on histones play essential roles in cell fate decisions during development. However, how these PTMs are recognized and coordinated remains to be fully illuminated. Here, we show that BRPF1, a multi-histone binding module protein, is essential for pluripotency...

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Detalles Bibliográficos
Autores principales: Zhang, Cong, Lin, Huaisong, Zhang, Yanqi, Xing, Qi, Zhang, Jingyuan, Zhang, Di, Liu, Yancai, Chen, Qianyu, Zhou, Tiancheng, Wang, Junwei, Shan, Yongli, Pan, Guangjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874078/
https://www.ncbi.nlm.nih.gov/pubmed/36711238
http://dx.doi.org/10.1016/j.isci.2023.105939