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Axin1 Protects Colon Carcinogenesis by an Immune-Mediated Effect

BACKGROUND & AIMS: Axin1 is a negative regulator of wingless-type MMTV integration site family, member 1 (Wnt)/β-catenin signaling with tumor-suppressor function. The Wnt pathway has a critical role in the intestine, both during homeostasis and cancer, but the role of Axin1 remains elusive. METH...

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Detalles Bibliográficos
Autores principales: Sanson, Romain, Lazzara, Silvia Luna, Cune, David, Pitasi, Caterina Luana, Trentesaux, Coralie, Fraudeau, Marie, Letourneur, Franck, Saintpierre, Benjamin, Le Gall, Morgane, Bossard, Pascale, Terris, Benoit, Finetti, Pascal, Bertucci, François, Mamessier, Emilie, Romagnolo, Béatrice, Perret, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874083/
https://www.ncbi.nlm.nih.gov/pubmed/36356835
http://dx.doi.org/10.1016/j.jcmgh.2022.10.017