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Axin1 Protects Colon Carcinogenesis by an Immune-Mediated Effect
BACKGROUND & AIMS: Axin1 is a negative regulator of wingless-type MMTV integration site family, member 1 (Wnt)/β-catenin signaling with tumor-suppressor function. The Wnt pathway has a critical role in the intestine, both during homeostasis and cancer, but the role of Axin1 remains elusive. METH...
Autores principales: | Sanson, Romain, Lazzara, Silvia Luna, Cune, David, Pitasi, Caterina Luana, Trentesaux, Coralie, Fraudeau, Marie, Letourneur, Franck, Saintpierre, Benjamin, Le Gall, Morgane, Bossard, Pascale, Terris, Benoit, Finetti, Pascal, Bertucci, François, Mamessier, Emilie, Romagnolo, Béatrice, Perret, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874083/ https://www.ncbi.nlm.nih.gov/pubmed/36356835 http://dx.doi.org/10.1016/j.jcmgh.2022.10.017 |
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