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Nasal administration of mesenchymal stem cells prevents accelerated age-related tauopathy after chemotherapy in mice

BACKGROUND: There is increasing concern that cancer and cancer treatment accelerate aging and the associated cognitive decline. We showed recently that treatment of 9-month-old male mice with cisplatin causes cognitive deficits that are associated with formation of tau deposits in the hippocampus. H...

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Detalles Bibliográficos
Autores principales: Zamorano, Miriam, Alexander, Jenolyn F., Catania, Desiree, Dharmaraj, Shruti, Kavelaars, Annemieke, Heijnen, Cobi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874182/
https://www.ncbi.nlm.nih.gov/pubmed/36698170
http://dx.doi.org/10.1186/s12979-023-00328-w