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Catalytic aza-Nazarov cyclization reactions to access α-methylene-γ-lactam heterocycles
We have developed a catalytic aza-Nazarov reaction of N-acyliminium salts generated in situ from the reaction of a variety of cyclic and acyclic imines with α,β-unsaturated acyl chlorides to afford substituted α-methylene-γ-lactam heterocycles. The reactions proceed effectively in the presence of ca...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874235/ https://www.ncbi.nlm.nih.gov/pubmed/36741815 http://dx.doi.org/10.3762/bjoc.19.6 |