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Catalytic aza-Nazarov cyclization reactions to access α-methylene-γ-lactam heterocycles

We have developed a catalytic aza-Nazarov reaction of N-acyliminium salts generated in situ from the reaction of a variety of cyclic and acyclic imines with α,β-unsaturated acyl chlorides to afford substituted α-methylene-γ-lactam heterocycles. The reactions proceed effectively in the presence of ca...

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Detalles Bibliográficos
Autores principales:	Yagci, Bilge Banu, Donmez, Selin Ezgi, Şahin, Onur, Türkmen, Yunus Emre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2023
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874235/ https://www.ncbi.nlm.nih.gov/pubmed/36741815 http://dx.doi.org/10.3762/bjoc.19.6

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