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Unusual phylogenetic tree and circulating actionable ESR1 mutations in an aggressive luminal/HER2-low breast cancer: Case report

Under therapeutic pressure aggressive tumors evolve rapidly. Herein, a luminal B/HER2-low breast cancer was tracked for >3 years during a total of 6 largely unsuccessful therapy lines, from adjuvant to advanced settings. Targeted next generation sequencing (NGS) of the primary lesion, two metasta...

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Detalles Bibliográficos
Autores principales: Allegretti, Matteo, Barberi, Vittoria, Ercolani, Cristiana, Vidiri, Antonello, Giordani, Elena, Ciliberto, Gennaro, Giacomini, Patrizio, Fabi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874630/
https://www.ncbi.nlm.nih.gov/pubmed/36713585
http://dx.doi.org/10.3389/fonc.2022.1050452