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Third-generation genome sequencing implicates medium-sized structural variants in chronic schizophrenia

BACKGROUND: Schizophrenia (SCZ) is a heterogeneous psychiatric disorder, with significant contribution from genetic factors particularly for chronic cases with negative symptoms and cognitive deficits. To date, Genome Wide Association Studies (GWAS) and exome sequencing have associated SCZ with a nu...

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Detalles Bibliográficos
Autores principales: Lee, Chi Chiu, Ye, Rui, Tubbs, Justin D., Baum, Larry, Zhong, Yuanxin, Leung, Shuk Yan Joey, Chan, Sheung Chun, Wu, Kit Ying Kitty, Cheng, Po Kwan Jamie, Chow, Lai Ping, Leung, Patrick W. L., Sham, Pak Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874699/
https://www.ncbi.nlm.nih.gov/pubmed/36711134
http://dx.doi.org/10.3389/fnins.2022.1058359