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Schistosomes contain divergent ligand-gated ion channels with an atypical Cys-loop motif

Ligand-gated ion channels (LGICs) are important regulators of neuromuscular function, making them attractive antiparasitic drug targets. While roundworm LGICs are targeted by several anthelmintic classes, flatworm LGICs are less studied. Chromosome-level genome assemblies have recently been released...

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Detalles Bibliográficos
Autores principales: Johnson, Hailey, VanHooreweghe, Mia, Satori, Jack A, Chan, John D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874803/
https://www.ncbi.nlm.nih.gov/pubmed/36713055
http://dx.doi.org/10.17912/micropub.biology.000694