BC‐11 is a covalent TMPRSS2 fragment inhibitor that impedes SARS‐CoV‐2 host cell entry

Host cell entry of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is facilitated via priming of its spike glycoprotein by the human transmembrane protease serine 2 (TMPRSS2). Although camostat and nafamostat are two highly potent covalent TMPRSS2 inhibitors, they nevertheless did not h...

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Detalles Bibliográficos
Autores principales: Moumbock, Aurélien F. A., Tran, Hoai T. T., Lamy, Evelyn, Günther, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874818/
https://www.ncbi.nlm.nih.gov/pubmed/36316225
http://dx.doi.org/10.1002/ardp.202200371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874818/
https://www.ncbi.nlm.nih.gov/pubmed/36316225
http://dx.doi.org/10.1002/ardp.202200371

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