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Nitric oxide synthase phosphorylation in fetoplacental endothelium is enhanced by agonism of Piezo1 mechanosensor in small for gestational age babies

Friction caused by blood flowing across cells that line blood vessels (endothelial cells) activates sensors of mechanical force. This produces nitric oxide (NO) which widens placental blood vessels, enabling more blood flow to the baby. This study sought to determine whether the mechanical sensor, P...

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Detalles Bibliográficos
Autores principales: Morley, L C, Debant, M, Gaunt, H J, Simpson, N A B, Beech, D J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874955/
https://www.ncbi.nlm.nih.gov/pubmed/36542598
http://dx.doi.org/10.1530/RAF-22-0100