Peripheral glucocorticoid receptor antagonism by relacorilant with modest HPA axis disinhibition

Glucocorticoid stress hormones are produced in response to hypothalamic–pituitary–adrenal (HPA) axis activation. Glucocorticoids are essential for physiology and exert numerous actions via binding to the glucocorticoid receptor (GR). Relacorilant is a highly selective GR antagonist currently undergo...

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Detalles Bibliográficos
Autores principales: Viho, Eva M G, Kroon, Jan, Feelders, Richard A, Houtman, René, van den Dungen, Elisabeth S R, Pereira, Alberto M, Hunt, Hazel J, Hofland, Leo J, Meijer, Onno C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874980/
https://www.ncbi.nlm.nih.gov/pubmed/36445262
http://dx.doi.org/10.1530/JOE-22-0263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9874980/
https://www.ncbi.nlm.nih.gov/pubmed/36445262
http://dx.doi.org/10.1530/JOE-22-0263

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