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Suppression of head and neck cancer cell survival and cisplatin resistance by GRP78 small molecule inhibitor YUM70

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer-related death worldwide. Surgical resection, radiation and chemotherapy are the mainstay of HNSCC treatment but are often unsatisfactory. Cisplatin is a commonly used chemotherapy in HNSCC; however, cisp...

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Detalles Bibliográficos
Autores principales: Yamamoto, Vicky, Wang, Bintao, Lee, Amy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875086/
https://www.ncbi.nlm.nih.gov/pubmed/36713577
http://dx.doi.org/10.3389/fonc.2022.1044699