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Efficacy and safety of switching from febuxostat to dotinurad, a novel selective urate reabsorption inhibitor, in hyperuricemic patients with type 2 diabetic kidney disease: Protocol for a single-arm, open-label, prospective, exploratory study

BACKGROUND: Dotinurad is a novel uricosuric drug in Japan with selective and potent urate transporter 1 (URAT1) inhibitory activity. This study aims to evaluate the efficacy and safety of dotinurad in hyperuricemic patients with type 2 diabetic kidney disease by comparing serum levels of urate and p...

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Detalles Bibliográficos
Autores principales: Osonoi, Takeshi, Saito, Miyoko, Hosoya, Mitsuru, Douguchi, Satako, Ofuchi, Kensuke, Katoh, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875127/
https://www.ncbi.nlm.nih.gov/pubmed/36714585
http://dx.doi.org/10.3389/fendo.2022.1042061