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PRKX down-regulates TAK1/IRF7 signaling in the antiviral innate immunity of black carp Mylopharyngodon piceus

TGF-β-activated kinase-1 (TAK1), tightly related to innate immunity, is phosphorylated and activated by X-linked protein kinase (PRKX) in humans and mammals, which belongs to the c-AMP-dependent protein kinase family. However, the relationship between PRKX and TAK1 remains unknown in teleost. It has...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Ai, Yue, Chen, Liang, Wang, Chanyuan, Liu, Ji, Zhang, Jie, Li, Jun, Wu, Hui, Xiao, Jun, Chang, Mingxian, Feng, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875139/
https://www.ncbi.nlm.nih.gov/pubmed/36713382
http://dx.doi.org/10.3389/fimmu.2022.999219