Mapping the Constrained Coding Regions in the Human Genome to Their Corresponding Proteins

Constrained Coding Regions (CCRs) in the human genome have been derived from DNA sequencing data of large cohorts of healthy control populations, available in the Genome Aggregation Database (gnomAD) [1]. They identify regions depleted of protein-changing variants and thus identify segments of the g...

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Detalles Bibliográficos
Autores principales: Hasenahuer, Marcia A., Sanchis-Juan, Alba, Laskowski, Roman A., Baker, James A., Stephenson, James D., Orengo, Christine A., Raymond, F. Lucy, Thornton, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875310/
https://www.ncbi.nlm.nih.gov/pubmed/36410474
http://dx.doi.org/10.1016/j.jmb.2022.167892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875310/
https://www.ncbi.nlm.nih.gov/pubmed/36410474
http://dx.doi.org/10.1016/j.jmb.2022.167892

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