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Mapping the Constrained Coding Regions in the Human Genome to Their Corresponding Proteins
Constrained Coding Regions (CCRs) in the human genome have been derived from DNA sequencing data of large cohorts of healthy control populations, available in the Genome Aggregation Database (gnomAD) [1]. They identify regions depleted of protein-changing variants and thus identify segments of the g...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875310/ https://www.ncbi.nlm.nih.gov/pubmed/36410474 http://dx.doi.org/10.1016/j.jmb.2022.167892 |