PET-based radiomics visualizes tumor-infiltrating CD8 T cell exhaustion to optimize radiotherapy/immunotherapy combination in mouse models of lung cancer

BACKGROUND: Cumulative preclinical and clinical evidences showed radiotherapy might augment systemic antitumoral responses to immunotherapy for metastatic non-small cell lung cancer, but the optimal timing of combination is still unclear. The overall infiltration and exhausted subpopulations of tumo...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Hu, Hui-Hui, Zhou, Shi-Hong, Xia, Wu-Yan, Zhang, Yan, Zhang, Jian-Ping, Fu, Xiao-Long, Yu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875413/
https://www.ncbi.nlm.nih.gov/pubmed/36694213
http://dx.doi.org/10.1186/s40364-023-00454-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875413/
https://www.ncbi.nlm.nih.gov/pubmed/36694213
http://dx.doi.org/10.1186/s40364-023-00454-z

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