Cargando…

MYEOV overexpression induced by demethylation of its promoter contributes to pancreatic cancer progression via activation of the folate cycle/c-Myc/mTORC1 pathway

BACKGROUND: While molecular targeted drugs and other therapies are being developed for many tumors, pancreatic cancer is still considered to be the malignant tumor with the worst prognosis. We started this study to identify prognostic genes and therapeutic targets of pancreatic cancer. METHODS: To c...

Descripción completa

Detalles Bibliográficos
Autores principales: Tange, Shoichiro, Hirano, Tomomi, Idogawa, Masashi, Hirata, Eishu, Imoto, Issei, Tokino, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875418/
https://www.ncbi.nlm.nih.gov/pubmed/36698109
http://dx.doi.org/10.1186/s12885-022-10433-6