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MYEOV overexpression induced by demethylation of its promoter contributes to pancreatic cancer progression via activation of the folate cycle/c-Myc/mTORC1 pathway
BACKGROUND: While molecular targeted drugs and other therapies are being developed for many tumors, pancreatic cancer is still considered to be the malignant tumor with the worst prognosis. We started this study to identify prognostic genes and therapeutic targets of pancreatic cancer. METHODS: To c...
Autores principales: | Tange, Shoichiro, Hirano, Tomomi, Idogawa, Masashi, Hirata, Eishu, Imoto, Issei, Tokino, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875418/ https://www.ncbi.nlm.nih.gov/pubmed/36698109 http://dx.doi.org/10.1186/s12885-022-10433-6 |
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