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Targeting Pim kinases in hematological cancers: molecular and clinical review

Decades of research has recognized a solid role for Pim kinases in lymphoproliferative disorders. Often up-regulated following JAK/STAT and tyrosine kinase receptor signaling, Pim kinases regulate cell proliferation, survival, metabolism, cellular trafficking and signaling. Targeting Pim kinases rep...

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Detalles Bibliográficos
Autores principales: Bellon, Marcia, Nicot, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875428/
https://www.ncbi.nlm.nih.gov/pubmed/36694243
http://dx.doi.org/10.1186/s12943-023-01721-1