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Targeting Pim kinases in hematological cancers: molecular and clinical review

Decades of research has recognized a solid role for Pim kinases in lymphoproliferative disorders. Often up-regulated following JAK/STAT and tyrosine kinase receptor signaling, Pim kinases regulate cell proliferation, survival, metabolism, cellular trafficking and signaling. Targeting Pim kinases rep...

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Detalles Bibliográficos
Autores principales:	Bellon, Marcia, Nicot, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875428/ https://www.ncbi.nlm.nih.gov/pubmed/36694243 http://dx.doi.org/10.1186/s12943-023-01721-1

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