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Transient inhibition of microsomal prostaglandin E synthase-1 after status epilepticus blunts brain inflammation and is neuroprotective

Status epilepticus (SE) in humans is characterized by prolonged convulsive seizures that are generalized and often difficult to control. The current antiseizure drugs (ASDs) aim to stop seizures quickly enough to prevent the SE-induced brain inflammation, injury, and long-term sequelae. However, sol...

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Detalles Bibliográficos
Autores principales: Yasmen, Nelufar, Sluter, Madison N., Li, Lexiao, Yu, Ying, Jiang, Jianxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875432/
https://www.ncbi.nlm.nih.gov/pubmed/36694204
http://dx.doi.org/10.1186/s13041-023-01008-y