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Prediction of protein solubility based on sequence physicochemical patterns and distributed representation information with DeepSoluE

BACKGROUND: Protein solubility is a precondition for efficient heterologous protein expression at the basis of most industrial applications and for functional interpretation in basic research. However, recurrent formation of inclusion bodies is still an inevitable roadblock in protein science and in...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Zou, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875434/
https://www.ncbi.nlm.nih.gov/pubmed/36694239
http://dx.doi.org/10.1186/s12915-023-01510-8