The clinical and genomic distinctions of Class1/2/3 BRAF-mutant colorectal cancer and differential prognoses

BRAF mutations are the oncogenic drivers in colorectal cancer and V600 mutations (Class1), which lead to RAS-independent active monomers, are the most common mutation types. BRAF non-V600 mutants can be further classified as RAS-independent active dimers (Class2) and RAS-dependent impaired kinase (C...

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Detalles Bibliográficos
Autores principales: Chen, Yungchang, Sun, Hao, Deng, Yanhong, Ma, Yutong, Huang, He, Liu, Yang, Zhang, Yaru, Zhang, Hongyu, Ye, Sheng, E, Mingyan, Guo, Hongqiang, Wu, Mengmeng, Wu, Chunman, Pu, Xingxiang, Chen, Xinggui, Liang, Chaoyong, Ou, Qiuxiang, Weng, Huawei, Wu, Xue, Shao, Yang, Gu, Anxin, Lin, Tongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875443/
https://www.ncbi.nlm.nih.gov/pubmed/36694231
http://dx.doi.org/10.1186/s40364-022-00443-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875443/
https://www.ncbi.nlm.nih.gov/pubmed/36694231
http://dx.doi.org/10.1186/s40364-022-00443-8

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