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β-actin mediated H3K27ac changes demonstrate the link between compartment switching and enhancer-dependent transcriptional regulation

BACKGROUND: Recent work has demonstrated that three-dimensional genome organization is directly affected by changes in the levels of nuclear cytoskeletal proteins such as β-actin. The mechanisms which translate changes in 3D genome structure into changes in transcription, however, are not fully unde...

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Detalles Bibliográficos
Autores principales: Mahmood, Syed Raza, Said, Nadine Hosny El, Gunsalus, Kristin C., Percipalle, Piergiorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875490/
https://www.ncbi.nlm.nih.gov/pubmed/36698204
http://dx.doi.org/10.1186/s13059-023-02853-9